Boost Your Immune System (or Not)

Is "boosting your immune system" for real? Is that possible, and can you really buy it in a bottle?

by Brian Dunning

Filed under Alternative Medicine, Consumer Ripoffs, Health

Skeptoid #227
October 12, 2010
Podcast transcript | Listen | Subscribe
Also available in German | Polish | Russian

Today we're going to point our skeptical eye at one of the most popular marketing gimmicks from the past few years: the sales of products and services with the claim that they will "boost your immune system". It sounds simple and desirable. Who wouldn't want a superpowered immune system capable of fighting off anything from a cold to cancer? Is such an ability really something you can buy in a bottle?

It's an easy claim to sell to people, because it's so clear and seems to make such obvious logical sense. The stronger your immune system, the greater its ability to fight disease. It sounds like it should be just like building muscle: A stronger bodybuilder can lift heavier weights, and a boosted immune system can fight off stronger diseases. Doesn't that sound right?

It may, but it's a completely invalid analogy. A healthy immune system is more accurately represented by a balanced teeter totter. If your immune system is compromised or otherwise weakened, one side of the teeter totter sags, and your body becomes more easily susceptible to infection. Conversely, if your immune system is overactive, the other side of the teeter totter sags, and the immune system attacks your own healthy tissues. This is what we call an autoimmune disease. Conditions like lupus, rheumatoid arthritis, psoriasis, and multiple sclerosis are all autoimmune diseases caused by "boosted", or overactive, immune systems. You're at your healthiest when the teeter totter of your immune system is balanced right in the center; neither too weak, nor too strong.

If you could boost your immune system, it would automatically and immediately be harmful.

So what do these companies mean when they claim their products boost the immune system? Fortunately for your body, they generally mean nothing at all. In recent years, the Federal Trade Commission and the Food and Drug Administration has been trying to crack down on products making unsubstantiated health claims, such as boosting the immune system. This is difficult for a number of reasons. First, "boosting your immune system" is medically meaningless; there is no such thing, so the assertion does not constitute a medical claim all by itself. You may recall that the supplement product Airborne was fined by the FTC and ordered to refund the money of everyone who had ever bought their product, but this was only because they went farther and specifically claimed their product could treat and prevent colds. Second, regulators are hopelessly outnumbered by the hordes of mail order and Internet businesses that can literally pop up overnight, to say nothing of the many well established companies like Airborne. Third, it's a very simple matter for such companies to subtly change their wording to make it even less specific, and thus escape prosecution. Today it's popular for products to say they "support a healthy immune system", and so they do, in the same way that any food or even breathing keeps your body alive and thus "supports" all its functions. They could just as honestly say their product supports body odor and aging.

Up until about ten years ago, nobody had invented the marketing term yet, so nobody ever thought to buy special supplements or specially grown produce to boost their immunity. Without such products, one wonders how the human race could have survived hundreds of thousands of years. Or even the 1980s or 1990s. Were we really less healthy then? Did we all truly have compromised immune systems?

You see, health is not the result of a superpowered immune system. Health is simply the absence of disease. Good health is the baseline. You can't be healthier than baseline. Once you're at the baseline, anything that happens to your immune system in either direction is bad. For a person in good health, who watches their diet and exercises, to walk into a smoothie store and order the special immunity boosting supplement, would be harmful to their health. Would be, if that supplement actually did anything.

It would be easy for companies to demonstrate that their products work as advertised. The immune system is a surprisingly complex collection of structures and processes throughout the body. Many of these are types of cells that can be found in the blood. If a product actually boosted your immune system, it would have to increase the counts of one or more of these cell types. That's something that we could measure directly, and prove or disprove the claim. The problem with doing such a test is that it would be unethical, since you would have to give someone an imbalance likely to result in an autoimmune disease.

Let's take a quick look at what some of these systems are:

All of those systems together comprise our "innate" immune systems, and they're just the half of it. We also have "adaptive" immune systems, and these are the systems that react to specific pathogens, multiply, and then become long-term guards against a recurrence of that same pathogen, becoming a sort of "memory" for your immune system. The adaptive immune system grows every time you challenge it with a specific germ, and it's also what reacts to a vaccine and becomes a prophylactic against a specific disease. The adaptive immune system is made up of special cells called lymphocytes, which include:

Those are the major components, but believe me, I've just given you an oversimplified 30,000-foot view of the immune system. Both halves, the innate and the adaptive, are comprised of many different components. Some act in concert, some act independently. There are many, many different ways in which parts of your immune system can be compromised, and addressing each of these deficiencies requires a different strategy. The notion that a single juice drink or supplement pill can "boost your immune system" is — to borrow a phrase — "so wrong it's not even wrong".

Since the function of the adaptive immune system is to react to challenges and develop new defenses, it can indeed be improved. Every time you catch a cold or get vaccinated, your adaptive immune system builds a new army of killer T cells ready to fight off a future recurrence of the same pathogen. There is no nutritional supplement, superfood, or mind/body/spirit technique that will do this for you. Those B cells only know which proteins to express by being attacked by specific disease agents.

Tip Skeptoid $2/mo $5/mo $10/mo One time

The usual response that I hear to these arguments is that "immune boosting" products are simply trying to restore healthy immune function, since we're all walking around with compromised immune systems, because we eat badly and are obese and live in a toxic world. This is a familiar argument, and it's also easy to sell. It sounds like it makes sense. People do overeat, we love our prepared foods, and few of us take any special interest in the chemicals making up the objects in our daily lives. Has this truly resulted in compromised immune systems?

In fact, the opposite is true. Obese people generally have inflammation, which is an immune response. We catch colds and have no difficulty in producing symptoms. When we're exposed to irritating substances, we react with hives or itching or asthma, all of which are immune responses. Practically every one of us has some immune system response going on right now. The claim that living in our modern world has compromised our immune systems is measurably, and unambiguously, untrue.

There are real conditions in which immune systems can be compromised. These include primary immunodeficiencies, which are usually genetic and exist from birth, and require complex medical intervention; and acquired immunodeficiencies, usually resulting from disease, like AIDS, some cancers, even chemotherapy. A specific component of the immune system is affected and requires a specific treatment. Acquired immunodeficiency can result from malnutrition, but you have to be practically starving to death. It's the opposite problem from eating too many cheeseburgers.

Supplements, juices, or any products that claim to "boost your immune system" are frauds. They are for-profit solutions to a problem that does not exist and was invented by clever marketers to scare you into buying the products. Don't stand for anyone telling you that your balanced teeter totter can be brought into better balance by piling sandbags on one end.

Brian Dunning

© 2010 Skeptoid Media Copyright information

References & Further Reading

Brain, M. "How Your Immune System Works." Discovery Health. Discovery Communications Inc., 1 Apr. 2000. Web. 8 Oct. 2010. <>

Crislip, M. "Boost Your Immune System?" Science-Based Medicine. Science-Based Medicine, 25 Sep. 2009. Web. 7 Oct. 2010. <>

Goldacre, B. "When it comes to a cold, you might as well try goat entrails." The Guardian. 22 Nov. 2008, Newspaper.

Hall, H. "Boost My Immune System? No Thanks!" Skeptic. 22 Mar. 2010, Volume 15, Number 4: 4-6.

Schindler, L. Understanding the Immune System. Washington, DC: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, 1988.

Singh, S., Ernst, E. Trick or Treatment. New York: W. W. Norton, 2008.

Wallace, A. "An Epidemic of Fear: How Panicked Parents Skipping Shots Endangers Us All." Wired. 1 Nov. 2009, Volume 17, Number 11.

Reference this article:
Dunning, B. "Boost Your Immune System (or Not)." Skeptoid Podcast. Skeptoid Media, 12 Oct 2010. Web. 4 Oct 2015. <>


10 most recent comments | Show all 179 comments

You got this one wrong, unfortunately. If not, then please explain how interferon cures hepatitis C in about 50% of patients infected with the virus (and don't say it boosts immune response, because apparently that is "meaningless"). Of course, I won't say that many supplements that claim to boost the immune system actually do anything, but the idea is scientifically valid.

Bob K., Austin, TX
May 3, 2013 7:10pm

Bob, that's a great point had we bothered to canvass how drugs work.

As to the idea being scientifically valid, anyone can posit anything. But you need empirical data to sell drugs, make a claim of efficacy (for reward) or even make the claim where others may review your work.

The notions that ideas arent examined are fallacies. They are exhaustively challenged and all you have to do is look them up.

I hope this isn't a show stopping comment as many of the claims (nearly all of the vitalism) deserve to be discussed in a skeptoid like this.

Mud, Sin City
May 3, 2013 10:26pm

All I'm saying is that "boosting your immune system" isn't meaningless. Interferon HAS exhaustive empirical evidence. So if a supplement were shown to increase interferon levels, it would be possible that it actually "boosts immune response" and therefore could help one fight off a viral infection. Have some supplements been shown to increase interferon levels? I can think of a couple that contain IFNs and/or have been shown to increase IFN levels. For example,

Bob K., Austin, TX
May 5, 2013 8:55pm

Bob K.

I personally benefited from a round of interferon treatment. I cleared the Hepatitis C virus in under 3 weeks.

All I can say is that I had never been sicker in my life. I asked my my doctor if I should get a flu shot, while undergoing treatment. The response I received from my doctor is that a flu shot is not medically necessary while on interferon because of the unknown mechanism of the treatment.

Bottom line, I don't think science fully understands how interferon treatment works.

Sara G, San Francisco, CA
December 16, 2013 6:33pm

This article is the biggest piece of bs I have every read. Obviously a paid shill for big pharma and Rockefeller medicine.

Tootsie, Mars
February 4, 2014 6:26pm

I agree, Tootsie. He thinks he's being scientific, but lacks wisdom and real knowledge. He probably even thinks caesarian birth is preferable to natural birth. He's obviously an intelligent guy. Yet he's terribly close-minded.
He's addicted to being right all the time, no matter what. What a waste of talent.

TB, Las Vegas
February 21, 2014 10:35am

Sounds like a clinician is writing this article. Anyone with any common sense would know in 5 minutes that we don't need highly complex therapies to treat disease.

It really is as simple as eating good food, not eating fake food, getting enough rest, and taking the proper food supplements that the body needs (whether that be vitamins, minerals, proteins, enzymes or whatever natural food that your body needs).

The absolute worst thing you can do is take pharmaceutical drugs, biochemical medicines, vaccines which destroy brain cells when the toxic adjuvants breach the blood brain barrier and can cause autism, diabetes, multiple sclerosis, and alzheimers, among other things.

After that long article explaining why I'm stupid and don't know anything, I think I'll just go mix up a protein drink with all those precious life-giving amino acids, throw in a little peanut butter, a couple ice cubes, my 1/4 cup scoop of protein, and add a banana, and I'll be good for the day!

Another homeschoolteacher Mom taught me this trick 35 years ago, and since then, I never get colds, flus or sore throats. I think her advice is working just fine, Thank You Very Much!

Why would God create an immune system that needed the help of poisonous vaccines to sustain homeostasis? That sounds counterproductive to me. Much better to eliminate all toxins, and give yourself good nutrition. The immune system will figure out it's own cure by itself!

JudgeDeborah, Dayton, Ohio
April 21, 2014 5:07am

Filgrastim boosts your immune system: it causes your bone marrow to throw additional stem cells into your blood.

It also hurts like an S.O.B.

It can be given to a bone marrow donor so the stem cells can be collected and injected to a person whose bone marrow has stopped producing health stem cells. The stem cells are given like a blood transfusion and if everything goes right they head right to the recipients bone marrow, settle in , and BINGO you have a brand new immune system and the cancer patient gets his/her life back. If it doesn't go right, either they don't work at all or they work so well they reject the recipient's body (host vs. graft disease) and the recipient dies.

Filgrastim is given to cancer patients whose immune system has been squashed by chemo.

An overactive immune system (Lupus) will also kill you.

For those Immune Sysem boosters you see in the store, well, better nutrition won't hurt.

Swampwitch7, Gainesville Fl
August 12, 2014 12:03pm

I agree with the core of the article, in that many unscrupulous supplement sellers will try to fool us and sell us useless crap.

That said, the concept of immune-modulation is scientifically valid. The immune response is triggered by elements (let's say pathogens) that the body sees as 'non-self' and tries to destroy.

These pathogens trigger receptors that in turn will cause T-cells, NK-cells etc. to be produced and do their work.

These receptors can also be triggered by non-pathogens, such as mushroom derived beta-glucans. These are acknowledged immune-modulators (which includes 'boosting' in case you wondered) but do not cause any harm themselves: being just chains of sugars (carbohydrates - polysaccharides). Read this Harvard publication:

By taking extracts based on medicinal mushrooms you can counter the negative effects of age and stress on the immune function. They modulate (not just 'boost') the immune function.

Make sure the percentage of beta-glucans is on the label, otherwise you'll end up buying expensive laxatives. Why ? These supplements should be extracts because raw mushrooms are indigestible.

The argument that boosting can lead to an overactive immune function (which is NOT good) is correct in itself, but only valid when using chemical boosters such as pharmaceutical drugs.
The beta-glucans are not able to push the immune function beyond its natural limits. 'Normalizing' is the max they can and do achieve.

Donald, Berlin, Germany
March 1, 2015 4:44am

I'm a big fan of this website as well as many other skeptic websites.
I sometimes find a tendency to not consider science with contrary evidence. Please watch this video to flesh out and perhaps balance the knowledge you received from Brian Dunning. See what you think.

Steve, NYC
July 2, 2015 10:13am

Make a comment about this episode of Skeptoid (please try to keep it brief & to the point).

Post a reply


What's the most important thing about Skeptoid?

Support Skeptoid

The Flying Saucer Menace
Skeptoid #486, Sep 29 2015
Read | Listen (12:29)
Holocaust Denial
Skeptoid #485, Sep 22 2015
Read | Listen (12:54)
More Unsung Women of Science
Skeptoid #484, Sep 15 2015
Read | Listen (12:56)
Unsung Women of Science
Skeptoid #483, Sep 8 2015
Read | Listen (13:13)
Sir Franklin's Cannibals
Skeptoid #482, Sep 1 2015
Read | Listen (12:13)
#1 -
The St. Clair Triangle UFO
Read | Listen
#2 -
Tube Amplifiers
Read | Listen
#3 -
Read | Listen
#4 -
That Elusive Fibromyalgia
Read | Listen
#5 -
SS Iron Mountain
Read | Listen
#6 -
A Skeptical Look at the News
Read | Listen
#7 -
The War of the Worlds Panic Broadcast
Read | Listen
#8 -
Ancient Astronauts
Read | Listen

Recent Comments...

[Valid RSS]

  Skeptoid PodcastSkeptoid on Facebook   Skeptoid on Twitter   Brian Dunning on Google+   Skeptoid on Stitcher   Skeptoid RSS

Members Portal


Follow @skeptoid

Tweets about skeptoid

Support Skeptoid

Email: [Why do we need this?]To reduce spam, we email new faces a confirmation link you must click before your comment will appear.
characters left. Abusive posts and spam will be deleted.